Skin Boosters vs. Polynucleotides: Which Is Right for You?
If you’re looking to achieve healthier, more youthful skin without the need for invasive treatments, you’ve probably come across skin boosters and polynucleotides. Both are amazing options for skin rejuvenation, but they work in slightly different ways. So, how do you know which one is right for you? Let’s break it down!
What Are Skin Boosters?
Skin boosters are hyaluronic acid (HA) injections designed to deeply hydrate the skin, improving its overall texture, elasticity, and glow. Unlike traditional dermal fillers, which add volume, skin boosters work by drawing moisture into the skin, making it look plumper and more radiant.
Key Benefits of Skin Boosters:
- Deep Hydration- Keeps the skin plump and dewy
- Improved Skin Elasticity – Helps with fine lines and crepiness
- Brighter, More Even Skin Tone – Gives a refreshed, glowing complexion
- Minimal Downtime – Quick treatment with little to no recovery time
Skin boosters are perfect if your skin feels dull, dehydrated, or in need of an overall boost. They’re particularly popular for the face, neck, and hands.

What Are Polynucleotides?
Polynucleotides (PNs) are the latest innovation in regenerative aesthetics. Unlike skin boosters, which focus on hydration, polynucleotides work at a deeper level by stimulating cell repair and collagen production. Derived from purified fish DNA, they act as biostimulators, encouraging your skin to heal, regenerate, and become firmer over time.
Key Benefits of Polynucleotides:
- Cellular Repair & Regeneration – Encourages new, healthy skin cell growth
- Boosts Collagen & Elastin – Improves firmness and elasticity
- Reduces Inflammation & Redness – Great for sensitive or damaged skin
- Long-Term Skin Quality Improvement – Results continue to develop over time
Polynucleotides are ideal for those experiencing skin laxity, acne scars, or early signs of aging. They’re also great for sensitive skin types and can even help with conditions like rosacea.

Skin Boosters vs. Polynucleotides: The Differences & Similarities
Feature | Skin Boosters | Polynucleotides |
Main Action | Hydrates & improves texture | Repairs & regenerates skin |
Key Ingredient | Hyaluronic Acid | Polynucleotide (fish-derived DNA) |
Best For | Dehydrated, dull skin | Damaged, aging, or inflamed skin |
Treatment Focus | Moisture retention & glow | Deep skin repair & anti-aging |
Results Timeline | Immediate glow, lasting 3-6 months | Gradual improvement over weeks/months |
Number of Sessions | 1-3 sessions | 3-4 sessions recommended |
Which One Should You Choose?
It really depends on your skin goals!
^ Go for skin boosters if: You want immediate hydration, a youthful glow, and smoother skin.
^ Go for polynucleotides if: You need deeper skin repair, improved elasticity, or long-term anti-aging benefits.
Some people even combine both treatments to maximise their results – skin boosters for instant hydration and plumpness, and polynucleotides for long-term skin regeneration.
Final Thoughts
Both skin boosters and polynucleotides are fantastic treatments for achieving healthy, youthful skin. Whether you want a quick glow-up or long-term skin repair, there’s a solution for you. If you’re unsure which is best for your skin type, book a consultation, and we’ll create a treatment plan tailored to your needs!
Want to learn more? Get in touch today!